STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rpmELarge subunit ribosomal protein l31; Binds the 23S rRNA (71 aa)    
Predicted Functional Partners:
rpmG
Large subunit ribosomal protein l33; Belongs to the bacterial ribosomal protein bL33 family
  
 
 0.999
rpmB
Large subunit ribosomal protein l28; Belongs to the bacterial ribosomal protein bL28 family
  
 
 0.999
rpmI
Large subunit ribosomal protein l35; Belongs to the bacterial ribosomal protein bL35 family
  
 
 0.999
rplT
Large subunit ribosomal protein l20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
 
 
 0.999
rpmH
Belongs to the bacterial ribosomal protein bL34 family
  
 
 0.998
rplV
Large subunit ribosomal protein l22; This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
  
 
 0.998
rplN
Large subunit ribosomal protein l14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
 
 
 0.998
rpmD
Large subunit ribosomal protein l30; rpmD_bact: ribosomal protein L30
   
 
 0.998
rplQ
Large subunit ribosomal protein l17; L17: ribosomal protein L17
  
 
 0.998
rplD
Large subunit ribosomal protein l4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity). Forms part of the polypeptide exit tunnel
 
   0.997
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 287
Other names: ATCC 10145, ATCC 10145-U, Bacillus aeruginosus, Bacillus pyocyaneus, Bacterium aeruginosum, Bacterium pyocyaneum, CCEB 481, CCUG 28447, CCUG 29297, CCUG 551, CFBP 2466, CIP 100720, DSM 50071, IBCS 277, IFO 12689, JCM 5962, Micrococcus pyocyaneus, NBRC 12689, NCCB 76039, NCIB 8295, NCIMB 8295, NCTC 10332, NRRL B-771, P. aeruginosa, Pseudomonas polycolor, Pseudomonas pyocyanea, Pseudomonas sp. RV3, RH 815, VKM B-588, bacterium ASFP-37, bacterium ASFP-38, bacterium ASFP-45, bacterium ASFP-46, bacterium ASFP-48
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