| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DR97_2583 | gcvH1 | DR97_2583 | DR97_5986 | gcvH- glycine cleavage system H protein | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein | 0.810 |
| DR97_2583 | gcvP1 | DR97_2583 | DR97_5987 | gcvH- glycine cleavage system H protein | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family | 0.999 |
| DR97_2583 | gcvP2 | DR97_2583 | DR97_2582 | gcvH- glycine cleavage system H protein | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family | 0.999 |
| DR97_2583 | gcvT1 | DR97_2583 | DR97_2584 | gcvH- glycine cleavage system H protein | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine | 0.999 |
| DR97_2583 | gcvT3 | DR97_2583 | DR97_5990 | gcvH- glycine cleavage system H protein | Aminomethyltransferase, mitochondrial; gcvT- glycine cleavage system T protein | 0.999 |
| DR97_2583 | glyA1 | DR97_2583 | DR97_2792 | gcvH- glycine cleavage system H protein | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism | 0.823 |
| DR97_2583 | glyA2 | DR97_2583 | DR97_1908 | gcvH- glycine cleavage system H protein | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism | 0.805 |
| DR97_2583 | glyA3 | DR97_2583 | DR97_5988 | gcvH- glycine cleavage system H protein | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism | 0.800 |
| DR97_2583 | soxA | DR97_2583 | DR97_2795 | gcvH- glycine cleavage system H protein | soxA- sarcosine oxidase, alpha subunit; Belongs to the GcvT family | 0.820 |
| gcvH1 | DR97_2583 | DR97_5986 | DR97_2583 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein | gcvH- glycine cleavage system H protein | 0.810 |
| gcvH1 | gcvP1 | DR97_5986 | DR97_5987 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family | 0.999 |
| gcvH1 | gcvP2 | DR97_5986 | DR97_2582 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family | 0.999 |
| gcvH1 | gcvT1 | DR97_5986 | DR97_2584 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine | 0.999 |
| gcvH1 | gcvT3 | DR97_5986 | DR97_5990 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein | Aminomethyltransferase, mitochondrial; gcvT- glycine cleavage system T protein | 0.999 |
| gcvH1 | glyA1 | DR97_5986 | DR97_2792 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism | 0.934 |
| gcvH1 | glyA2 | DR97_5986 | DR97_1908 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism | 0.881 |
| gcvH1 | glyA3 | DR97_5986 | DR97_5988 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism | 0.949 |
| gcvH1 | soxA | DR97_5986 | DR97_2795 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein | soxA- sarcosine oxidase, alpha subunit; Belongs to the GcvT family | 0.820 |
| gcvH_2 | gcvP1 | DR97_2141 | DR97_5987 | annotation not available | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family | 0.994 |
| gcvH_2 | gcvP2 | DR97_2141 | DR97_2582 | annotation not available | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family | 0.995 |
