node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DR97_2700 | pyrE | DR97_2700 | DR97_2702 | Hypothetical protein; DUF4124 domain-containing protein | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) | 0.857 |
carA | carB | DR97_2102 | DR97_2100 | Carbamoyl-phosphate synthase small subunit; Belongs to the CarA family | CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family | 0.999 |
carA | guaA | DR97_2102 | DR97_4101 | Carbamoyl-phosphate synthase small subunit; Belongs to the CarA family | Bifunctional gmp synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP | 0.669 |
carA | purL | DR97_2102 | DR97_4112 | Carbamoyl-phosphate synthase small subunit; Belongs to the CarA family | Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate | 0.717 |
carA | pyrB | DR97_2102 | DR97_3370 | Carbamoyl-phosphate synthase small subunit; Belongs to the CarA family | Aspartate carbamoyltransferase catalytic subunit; Asp_carb_tr: aspartate carbamoyltransferase; Belongs to the ATCase/OTCase family | 0.999 |
carA | pyrD | DR97_2102 | DR97_4886 | Carbamoyl-phosphate synthase small subunit; Belongs to the CarA family | Dihydroorotate dehydrogenase 2; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor | 0.736 |
carA | pyrE | DR97_2102 | DR97_2702 | Carbamoyl-phosphate synthase small subunit; Belongs to the CarA family | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) | 0.959 |
carA | pyrF | DR97_2102 | DR97_5065 | Carbamoyl-phosphate synthase small subunit; Belongs to the CarA family | Orotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP) | 0.957 |
carB | carA | DR97_2100 | DR97_2102 | CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family | Carbamoyl-phosphate synthase small subunit; Belongs to the CarA family | 0.999 |
carB | guaA | DR97_2100 | DR97_4101 | CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family | Bifunctional gmp synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP | 0.973 |
carB | purL | DR97_2100 | DR97_4112 | CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family | Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate | 0.979 |
carB | pyrB | DR97_2100 | DR97_3370 | CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family | Aspartate carbamoyltransferase catalytic subunit; Asp_carb_tr: aspartate carbamoyltransferase; Belongs to the ATCase/OTCase family | 0.999 |
carB | pyrD | DR97_2100 | DR97_4886 | CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family | Dihydroorotate dehydrogenase 2; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor | 0.960 |
carB | pyrE | DR97_2100 | DR97_2702 | CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) | 0.979 |
carB | pyrF | DR97_2100 | DR97_5065 | CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family | Orotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP) | 0.994 |
guaA | carA | DR97_4101 | DR97_2102 | Bifunctional gmp synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP | Carbamoyl-phosphate synthase small subunit; Belongs to the CarA family | 0.669 |
guaA | carB | DR97_4101 | DR97_2100 | Bifunctional gmp synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP | CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family | 0.973 |
guaA | prs | DR97_4101 | DR97_1980 | Bifunctional gmp synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P) | 0.857 |
guaA | purL | DR97_4101 | DR97_4112 | Bifunctional gmp synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP | Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate | 0.991 |
guaA | pyrB | DR97_4101 | DR97_3370 | Bifunctional gmp synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP | Aspartate carbamoyltransferase catalytic subunit; Asp_carb_tr: aspartate carbamoyltransferase; Belongs to the ATCase/OTCase family | 0.839 |