| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| FumA | sdhA | DR97_1509 | DR97_306 | Hydrolyase, tartrate alpha subunit/fumarate, fe-s type domain protein; Catalyzes the reversible hydration of fumarate to (S)-malate | Succinate dehydrogenase / fumarate reductase, flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily | 0.990 |
| FumA | sdhB | DR97_1509 | DR97_305 | Hydrolyase, tartrate alpha subunit/fumarate, fe-s type domain protein; Catalyzes the reversible hydration of fumarate to (S)-malate | dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur family protein | 0.968 |
| FumA | sdhC | DR97_1509 | DR97_308 | Hydrolyase, tartrate alpha subunit/fumarate, fe-s type domain protein; Catalyzes the reversible hydration of fumarate to (S)-malate | Succinate dehydrogenase / fumarate reductase, cytochrome b subunit; succ_dehyd_cytB: succinate dehydrogenase, cytochrome b556 subunit | 0.997 |
| FumA | sdhD | DR97_1509 | DR97_307 | Hydrolyase, tartrate alpha subunit/fumarate, fe-s type domain protein; Catalyzes the reversible hydration of fumarate to (S)-malate | Succinate dehydrogenase / fumarate reductase, membrane anchor subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) | 0.986 |
| FumA | sucA | DR97_1509 | DR97_304 | Hydrolyase, tartrate alpha subunit/fumarate, fe-s type domain protein; Catalyzes the reversible hydration of fumarate to (S)-malate | 2oxo_dh_E1: oxoglutarate dehydrogenase (succinyl-transferring), E1 component | 0.907 |
| FumA | sucC | DR97_1509 | DR97_301 | Hydrolyase, tartrate alpha subunit/fumarate, fe-s type domain protein; Catalyzes the reversible hydration of fumarate to (S)-malate | Succinyl-coa ligase [adp-forming] subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. Can also generate UTP or CTP, although it preferentially synthesizes ATP and/or GTP | 0.792 |
| FumA | sucD | DR97_1509 | DR97_300 | Hydrolyase, tartrate alpha subunit/fumarate, fe-s type domain protein; Catalyzes the reversible hydration of fumarate to (S)-malate | Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. Can also generate UTP or CTP, although it preferentially synthesizes ATP and/or GTP | 0.915 |
| cyoA | cyoB | DR97_477 | DR97_476 | Cytochrome o ubiquinol oxidase subunit ii; Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron (By similarity) | Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron (By similarity) | 0.999 |
| cyoA | cyoD | DR97_477 | DR97_474 | Cytochrome o ubiquinol oxidase subunit ii; Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron (By similarity) | Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron (By similarity) | 0.999 |
| cyoA | sdhA | DR97_477 | DR97_306 | Cytochrome o ubiquinol oxidase subunit ii; Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron (By similarity) | Succinate dehydrogenase / fumarate reductase, flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily | 0.936 |
| cyoA | sdhB | DR97_477 | DR97_305 | Cytochrome o ubiquinol oxidase subunit ii; Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron (By similarity) | dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur family protein | 0.937 |
| cyoA | sdhC | DR97_477 | DR97_308 | Cytochrome o ubiquinol oxidase subunit ii; Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron (By similarity) | Succinate dehydrogenase / fumarate reductase, cytochrome b subunit; succ_dehyd_cytB: succinate dehydrogenase, cytochrome b556 subunit | 0.966 |
| cyoA | sdhD | DR97_477 | DR97_307 | Cytochrome o ubiquinol oxidase subunit ii; Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron (By similarity) | Succinate dehydrogenase / fumarate reductase, membrane anchor subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) | 0.963 |
| cyoA | sucA | DR97_477 | DR97_304 | Cytochrome o ubiquinol oxidase subunit ii; Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron (By similarity) | 2oxo_dh_E1: oxoglutarate dehydrogenase (succinyl-transferring), E1 component | 0.496 |
| cyoB | cyoA | DR97_476 | DR97_477 | Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron (By similarity) | Cytochrome o ubiquinol oxidase subunit ii; Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron (By similarity) | 0.999 |
| cyoB | cyoD | DR97_476 | DR97_474 | Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron (By similarity) | Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron (By similarity) | 0.999 |
| cyoB | sdhA | DR97_476 | DR97_306 | Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron (By similarity) | Succinate dehydrogenase / fumarate reductase, flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily | 0.950 |
| cyoB | sdhB | DR97_476 | DR97_305 | Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron (By similarity) | dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur family protein | 0.949 |
| cyoB | sdhC | DR97_476 | DR97_308 | Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron (By similarity) | Succinate dehydrogenase / fumarate reductase, cytochrome b subunit; succ_dehyd_cytB: succinate dehydrogenase, cytochrome b556 subunit | 0.964 |
| cyoB | sdhD | DR97_476 | DR97_307 | Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron (By similarity) | Succinate dehydrogenase / fumarate reductase, membrane anchor subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) | 0.962 |
STRING Database User Survey
