STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pyrC'Multifunctional complex type domain protein; pyrC_multi: dihydroorotase, multifunctional complex type domain protein (423 aa)    
Predicted Functional Partners:
pyrB
Asp_carb_tr: aspartate carbamoyltransferase; Belongs to the ATCase/OTCase family
 0.999
pyrR
Bifunctional protein PyrR; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
 
 
 0.974
pyrD
Dihydroorotate dehydrogenase (quinone); Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
  
 0.949
carB
CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family
 
 0.914
carA
CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family
  
 0.902
DR97_4415
Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate
    
 0.840
pyrQ
annotation not available
  
  
 
0.836
pyrF
Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily
  
  
 0.829
metF
Fadh2: 5,10-methylenetetrahydrofolate reductase
  
    0.728
yqgF
Putative pre-16S rRNA nuclease; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
  
    0.686
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 287
Other names: ATCC 10145, ATCC 10145-U, Bacillus aeruginosus, Bacillus pyocyaneus, Bacterium aeruginosum, Bacterium pyocyaneum, CCEB 481, CCUG 28447, CCUG 29297, CCUG 551, CFBP 2466, CIP 100720, DSM 50071, IBCS 277, IFO 12689, JCM 5962, Micrococcus pyocyaneus, NBRC 12689, NCCB 76039, NCIB 8295, NCIMB 8295, NCTC 10332, NRRL B-771, P. aeruginosa, Pseudomonas aeruginosa, Pseudomonas polycolor, Pseudomonas pyocyanea, Pseudomonas sp. RV3, RH 815, VKM B-588, bacterium ASFP-37, bacterium ASFP-38, bacterium ASFP-45, bacterium ASFP-46, bacterium ASFP-48
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