node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AmrB | DR97_1551 | DR97_5829 | DR97_1551 | 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 family protein | Membrane fusion protein, multidrug efflux system; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family | 0.988 |
AmrB | DR97_5828 | DR97_5829 | DR97_5828 | 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 family protein | Membrane fusion protein, multidrug efflux system; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family | 0.999 |
AmrB | macB | DR97_5829 | DR97_6042 | 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 family protein | Macrolide transport system atp-binding/permease protein; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides | 0.889 |
AmrB | mexA | DR97_5829 | DR97_3393 | 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 family protein | Membrane fusion protein, multidrug efflux system; The periplasmic linker component of the MexAB-OprM efflux system that confers multidrug resistance. Also functions as the major efflux pump for n-hexane and p-xylene efflux. Over-expression of the pump increases antibiotic and solvent efflux capacities. Required for assembly of the MexA/MexB/OprM complex. Implicated in the secretion of the siderophore pyoverdine | 0.995 |
AmrB | mexB | DR97_5829 | DR97_3394 | 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 family protein | Multidrug resistance protein mexb; The inner membrane transporter component of the MexAB-OprM efflux system that confers multidrug resistance. Also functions as the major efflux pump for n-hexane and p-xylene efflux. Over-expression of the pump increases antibiotic and solvent efflux capacities. Implicated in the secretion of the siderophore pyoverdine | 0.817 |
AmrB | mexC | DR97_5829 | DR97_1905 | 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 family protein | Membrane fusion protein, multidrug efflux system; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family | 0.994 |
AmrB | mexE | DR97_5829 | DR97_5679 | 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 family protein | Membrane fusion protein, multidrug efflux system; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family | 0.884 |
AmrB | oprM | DR97_5829 | DR97_3395 | 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 family protein | Major intrinsic multiple antibiotic resistance efflux outer membrane protein; The outer membrane component of the MexAB-OprM efflux system that confers multidrug resistance. Also functions as the major efflux pump for n-hexane and p-xylene efflux. Over-expression of the pump increases antibiotic and solvent efflux capacities. Can replace the OprJ outer membrane component of the MexCD-OprJ pump; the antibiotics exported are those exported by the intact MexCD pump, showing that efflux substrate specificity is not conferred by this component. Serves as the outer membrane component for the [...] | 0.987 |
DR97_1551 | AmrB | DR97_1551 | DR97_5829 | Membrane fusion protein, multidrug efflux system; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family | 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 family protein | 0.988 |
DR97_1551 | DR97_5828 | DR97_1551 | DR97_5828 | Membrane fusion protein, multidrug efflux system; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family | Membrane fusion protein, multidrug efflux system; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family | 0.802 |
DR97_1551 | MexF | DR97_1551 | DR97_4420 | Membrane fusion protein, multidrug efflux system; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family | 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 family protein | 0.775 |
DR97_1551 | macB | DR97_1551 | DR97_6042 | Membrane fusion protein, multidrug efflux system; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family | Macrolide transport system atp-binding/permease protein; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides | 0.982 |
DR97_1551 | mexA | DR97_1551 | DR97_3393 | Membrane fusion protein, multidrug efflux system; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family | Membrane fusion protein, multidrug efflux system; The periplasmic linker component of the MexAB-OprM efflux system that confers multidrug resistance. Also functions as the major efflux pump for n-hexane and p-xylene efflux. Over-expression of the pump increases antibiotic and solvent efflux capacities. Required for assembly of the MexA/MexB/OprM complex. Implicated in the secretion of the siderophore pyoverdine | 0.866 |
DR97_1551 | mexB | DR97_1551 | DR97_3394 | Membrane fusion protein, multidrug efflux system; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family | Multidrug resistance protein mexb; The inner membrane transporter component of the MexAB-OprM efflux system that confers multidrug resistance. Also functions as the major efflux pump for n-hexane and p-xylene efflux. Over-expression of the pump increases antibiotic and solvent efflux capacities. Implicated in the secretion of the siderophore pyoverdine | 0.983 |
DR97_1551 | mexD | DR97_1551 | DR97_1904 | Membrane fusion protein, multidrug efflux system; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family | 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 family protein | 0.944 |
DR97_1551 | oprM | DR97_1551 | DR97_3395 | Membrane fusion protein, multidrug efflux system; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family | Major intrinsic multiple antibiotic resistance efflux outer membrane protein; The outer membrane component of the MexAB-OprM efflux system that confers multidrug resistance. Also functions as the major efflux pump for n-hexane and p-xylene efflux. Over-expression of the pump increases antibiotic and solvent efflux capacities. Can replace the OprJ outer membrane component of the MexCD-OprJ pump; the antibiotics exported are those exported by the intact MexCD pump, showing that efflux substrate specificity is not conferred by this component. Serves as the outer membrane component for the [...] | 0.988 |
DR97_5828 | AmrB | DR97_5828 | DR97_5829 | Membrane fusion protein, multidrug efflux system; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family | 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 family protein | 0.999 |
DR97_5828 | DR97_1551 | DR97_5828 | DR97_1551 | Membrane fusion protein, multidrug efflux system; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family | Membrane fusion protein, multidrug efflux system; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family | 0.802 |
DR97_5828 | MexF | DR97_5828 | DR97_4420 | Membrane fusion protein, multidrug efflux system; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family | 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 family protein | 0.926 |
DR97_5828 | macB | DR97_5828 | DR97_6042 | Membrane fusion protein, multidrug efflux system; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family | Macrolide transport system atp-binding/permease protein; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides | 0.903 |