ygdH protein (Pseudomonas aeruginosa) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
some 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

ygdH

LOG family protein ygdH; Protein containing a predicted nucleotide-binding domain of Rossmann fold (461 aa)

Predicted Functional Partners:

mazG

0.909

add

0.902

codA

0.902

cpdA

0.902

adk

0.902

DR97_2545

0.900

surE

0.900

cmk

0.900

ppnP

0.900

nuh

0.900

Your Current Organism:

Pseudomonas aeruginosa

NCBI taxonomy Id: 287
Other names: ATCC 10145, ATCC 10145-U, Bacillus aeruginosus, Bacillus pyocyaneus, Bacterium aeruginosum, Bacterium pyocyaneum, CCEB 481, CCUG 28447, CCUG 29297, CCUG 551, CFBP 2466, CIP 100720, DSM 50071, IBCS 277, IFO 12689, JCM 5962, Micrococcus pyocyaneus, NBRC 12689, NCCB 76039, NCIB 8295, NCIMB 8295, NCTC 10332, NRRL B-771, P. aeruginosa, Pseudomonas aeruginosa, Pseudomonas polycolor, Pseudomonas pyocyanea, Pseudomonas sp. RV3, RH 815, VKM B-588, bacterium ASFP-37, bacterium ASFP-38, bacterium ASFP-45, bacterium ASFP-46, bacterium ASFP-48

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but resolution at 400 dpi

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as simple tabular text output:

download

TSV: tab separated values - can be opened in Excel

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DR97_2545	adk	DR97_2545	DR97_4191	Hydrolase; HAD-SF-IA-v3- HAD hydrolase, IA, variant 3 family protein	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family	0.902
DR97_2545	cmk	DR97_2545	DR97_4773	Hydrolase; HAD-SF-IA-v3- HAD hydrolase, IA, variant 3 family protein	Cmk- cytidylate kinase; Belongs to the cytidylate kinase family. Type 1 subfamily	0.902
DR97_2545	cpdA	DR97_2545	DR97_2322	Hydrolase; HAD-SF-IA-v3- HAD hydrolase, IA, variant 3 family protein	3’,5’-cyclic adenosine monophosphate phosphodiesterase CpdA; Hydrolyzes cAMP to 5’-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. Specifically required for regulation of virulence factors. Can also hydrolyze cGMP; Belongs to the cAMP phosphodiesterase class-III family	0.918
DR97_2545	mazG	DR97_2545	DR97_1004	Hydrolase; HAD-SF-IA-v3- HAD hydrolase, IA, variant 3 family protein	Nucleoside triphosphate pyrophosphohydrolase; mazG- MazG family protein	0.903
DR97_2545	nuh	DR97_2545	DR97_3100	Hydrolase; HAD-SF-IA-v3- HAD hydrolase, IA, variant 3 family protein	annotation not available	0.902
DR97_2545	ppnP	DR97_2545	DR97_361	Hydrolase; HAD-SF-IA-v3- HAD hydrolase, IA, variant 3 family protein	Pyrimidine/purine nucleoside phosphorylase; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions	0.900
DR97_2545	surE	DR97_2545	DR97_4314	Hydrolase; HAD-SF-IA-v3- HAD hydrolase, IA, variant 3 family protein	5’-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5’-monophosphates; Belongs to the SurE nucleotidase family	0.804
DR97_2545	ygdH	DR97_2545	DR97_3756	Hydrolase; HAD-SF-IA-v3- HAD hydrolase, IA, variant 3 family protein	LOG family protein ygdH; Protein containing a predicted nucleotide-binding domain of Rossmann fold	0.900
add	codA	DR97_3105	DR97_3405	Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism	annotation not available	0.886
add	nuh	DR97_3105	DR97_3100	Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism	annotation not available	0.944
add	ppnP	DR97_3105	DR97_361	Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism	Pyrimidine/purine nucleoside phosphorylase; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions	0.907
add	ygdH	DR97_3105	DR97_3756	Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism	LOG family protein ygdH; Protein containing a predicted nucleotide-binding domain of Rossmann fold	0.902
adk	DR97_2545	DR97_4191	DR97_2545	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family	Hydrolase; HAD-SF-IA-v3- HAD hydrolase, IA, variant 3 family protein	0.902
adk	cpdA	DR97_4191	DR97_2322	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family	3’,5’-cyclic adenosine monophosphate phosphodiesterase CpdA; Hydrolyzes cAMP to 5’-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. Specifically required for regulation of virulence factors. Can also hydrolyze cGMP; Belongs to the cAMP phosphodiesterase class-III family	0.902
adk	mazG	DR97_4191	DR97_1004	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family	Nucleoside triphosphate pyrophosphohydrolase; mazG- MazG family protein	0.933
adk	surE	DR97_4191	DR97_4314	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family	5’-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5’-monophosphates; Belongs to the SurE nucleotidase family	0.917
adk	ygdH	DR97_4191	DR97_3756	Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family	LOG family protein ygdH; Protein containing a predicted nucleotide-binding domain of Rossmann fold	0.902
cmk	DR97_2545	DR97_4773	DR97_2545	Cmk- cytidylate kinase; Belongs to the cytidylate kinase family. Type 1 subfamily	Hydrolase; HAD-SF-IA-v3- HAD hydrolase, IA, variant 3 family protein	0.902
cmk	mazG	DR97_4773	DR97_1004	Cmk- cytidylate kinase; Belongs to the cytidylate kinase family. Type 1 subfamily	Nucleoside triphosphate pyrophosphohydrolase; mazG- MazG family protein	0.916
cmk	surE	DR97_4773	DR97_4314	Cmk- cytidylate kinase; Belongs to the cytidylate kinase family. Type 1 subfamily	5’-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5’-monophosphates; Belongs to the SurE nucleotidase family	0.921

page 1 of 4

Network

Neighborhood

Experiments

Cooccurrence

Databases

Coexpression

Textmining

Fusion

© STRING Consortium 2020

Credits

Access

Info

About