Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
query proteins and first shell of interactors
second shell of interactors
proteins of unknown 3D structure
some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
|rlmH||Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (155 aa)|| |
Predicted Functional Partners:
Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
| || || ||0.998
Catalyzes cross-linking of the peptidoglycan cell wall.
| || || || ||0.983
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
| || || || || ||0.952
Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
| || || || || ||0.949
Specifically methylates guanosine-37 in various tRNAs.
| || || || || ||0.934
Methylates ribosomal protein L11
| || || || || ||0.932
Peptidoglycan polymerase that is essential for cell wall elongation
| || || || || ||0.931
Specifically methylates the ribose of guanosine 2251 in 23S rRNA
| || || || ||0.922
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity
| || || || || ||0.904
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
| || || || || ||0.900
Your Current Organism:
NCBI taxonomy Id: 287
Other names: ATCC 10145, ATCC 10145-U, Bacillus aeruginosus, Bacillus pyocyaneus, Bacterium aeruginosum, Bacterium pyocyaneum, CCEB 481, CCUG 28447, CCUG 29297, CCUG 551, CFBP 2466, CIP 100720, DSM 50071, IBCS 277, IFO 12689, JCM 5962, Micrococcus pyocyaneus, NBRC 12689, NCCB 76039, NCIB 8295, NCIMB 8295, NCTC 10332, NRRL B-771, P. aeruginosa, Pseudomonas polycolor, Pseudomonas pyocyanea, Pseudomonas sp. RV3, RH 815, VKM B-588, bacterium ASFP-37, bacterium ASFP-38, bacterium ASFP-45, bacterium ASFP-46, bacterium ASFP-48
Server load: low (4%) [HD]