STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mrdBPeptidoglycan polymerase that is essential for cell wall elongation (381 aa)    
Predicted Functional Partners:
mrdA
Catalyzes cross-linking of the peptidoglycan cell wall.
 
 0.999
mreC
Involved in formation and maintenance of cell shape.
 
 
 0.992
mreB
annotation not available
 
 0.992
DR97_3867
Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
 
 
 0.986
dacC
Belongs to the peptidase S11 family.
 
 
 0.973
ftsI
Catalyzes cross-linking of the peptidoglycan cell wall at the division septum (By similarity). Binds penicillin .
 
 0.955
sltB1
mltB: lytic murein transglycosylase B
  
 
 0.946
mreD
Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins.
  
  
 0.943
pbpC
Catalyzes cross-linking of the peptidoglycan cell wall at the division septum (By similarity). Binds penicillin .
 
 0.942
rlmH
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
 
    0.931
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 287
Other names: ATCC 10145, ATCC 10145-U, Bacillus aeruginosus, Bacillus pyocyaneus, Bacterium aeruginosum, Bacterium pyocyaneum, CCEB 481, CCUG 28447, CCUG 29297, CCUG 551, CFBP 2466, CIP 100720, DSM 50071, IBCS 277, IFO 12689, JCM 5962, Micrococcus pyocyaneus, NBRC 12689, NCCB 76039, NCIB 8295, NCIMB 8295, NCTC 10332, NRRL B-771, P. aeruginosa, Pseudomonas polycolor, Pseudomonas pyocyanea, Pseudomonas sp. RV3, RH 815, VKM B-588, bacterium ASFP-37, bacterium ASFP-38, bacterium ASFP-45, bacterium ASFP-46, bacterium ASFP-48
Server load: low (4%) [HD]