node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
apaG | engA | DR97_3560 | DR97_4070 | Hypothetical protein; Protein ApaG | Ribosome-associated gtpase enga; GTPase that plays an essential role in the late steps of ribosome biogenesis | 0.866 |
apaG | rsmH | DR97_3560 | DR97_1598 | Hypothetical protein; Protein ApaG | 16S rRNA (cytosine(1402)-N(4))-methyltransferase; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA | 0.722 |
cgtA | cmk | DR97_1870 | DR97_4773 | Obg family gtpase cgta; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control | Cmk: cytidylate kinase; Belongs to the cytidylate kinase family. Type 1 subfamily | 0.436 |
cgtA | engA | DR97_1870 | DR97_4070 | Obg family gtpase cgta; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control | Ribosome-associated gtpase enga; GTPase that plays an essential role in the late steps of ribosome biogenesis | 0.922 |
cgtA | rplD | DR97_1870 | DR97_3649 | Obg family gtpase cgta; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control | Large subunit ribosomal protein l4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity). Forms part of the polypeptide exit tunnel | 0.837 |
cgtA | rplO | DR97_1870 | DR97_3667 | Obg family gtpase cgta; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control | Large subunit ribosomal protein l15; Binds to the 23S rRNA | 0.827 |
cgtA | rplT | DR97_1870 | DR97_5221 | Obg family gtpase cgta; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control | Large subunit ribosomal protein l20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit | 0.885 |
cgtA | rplV | DR97_1870 | DR97_3653 | Obg family gtpase cgta; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control | Large subunit ribosomal protein l22; This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity) | 0.896 |
cgtA | rsmH | DR97_1870 | DR97_1598 | Obg family gtpase cgta; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control | 16S rRNA (cytosine(1402)-N(4))-methyltransferase; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA | 0.732 |
cmk | cgtA | DR97_4773 | DR97_1870 | Cmk: cytidylate kinase; Belongs to the cytidylate kinase family. Type 1 subfamily | Obg family gtpase cgta; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control | 0.436 |
cmk | engA | DR97_4773 | DR97_4070 | Cmk: cytidylate kinase; Belongs to the cytidylate kinase family. Type 1 subfamily | Ribosome-associated gtpase enga; GTPase that plays an essential role in the late steps of ribosome biogenesis | 0.902 |
cmk | hisS | DR97_4773 | DR97_4067 | Cmk: cytidylate kinase; Belongs to the cytidylate kinase family. Type 1 subfamily | Histidyl-trna synthetase; hisS: histidine--tRNA ligase | 0.506 |
cmk | rplV | DR97_4773 | DR97_3653 | Cmk: cytidylate kinase; Belongs to the cytidylate kinase family. Type 1 subfamily | Large subunit ribosomal protein l22; This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity) | 0.558 |
engA | apaG | DR97_4070 | DR97_3560 | Ribosome-associated gtpase enga; GTPase that plays an essential role in the late steps of ribosome biogenesis | Hypothetical protein; Protein ApaG | 0.866 |
engA | cgtA | DR97_4070 | DR97_1870 | Ribosome-associated gtpase enga; GTPase that plays an essential role in the late steps of ribosome biogenesis | Obg family gtpase cgta; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control | 0.922 |
engA | cmk | DR97_4070 | DR97_4773 | Ribosome-associated gtpase enga; GTPase that plays an essential role in the late steps of ribosome biogenesis | Cmk: cytidylate kinase; Belongs to the cytidylate kinase family. Type 1 subfamily | 0.902 |
engA | hisS | DR97_4070 | DR97_4067 | Ribosome-associated gtpase enga; GTPase that plays an essential role in the late steps of ribosome biogenesis | Histidyl-trna synthetase; hisS: histidine--tRNA ligase | 0.952 |
engA | rplD | DR97_4070 | DR97_3649 | Ribosome-associated gtpase enga; GTPase that plays an essential role in the late steps of ribosome biogenesis | Large subunit ribosomal protein l4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity). Forms part of the polypeptide exit tunnel | 0.852 |
engA | rplO | DR97_4070 | DR97_3667 | Ribosome-associated gtpase enga; GTPase that plays an essential role in the late steps of ribosome biogenesis | Large subunit ribosomal protein l15; Binds to the 23S rRNA | 0.855 |
engA | rplT | DR97_4070 | DR97_5221 | Ribosome-associated gtpase enga; GTPase that plays an essential role in the late steps of ribosome biogenesis | Large subunit ribosomal protein l20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit | 0.863 |