STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mmsBHIBADH: 3-hydroxyisobutyrate dehydrogenase; Belongs to the 3-hydroxyisobutyrate dehydrogenase family (298 aa)    
Predicted Functional Partners:
mmsA
Malonate-semialdehyde dehydrogenase (acetylating) / methylmalonate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family
 
 0.999
DR97_1237
Malonate-semialdehyde dehydrogenase (acetylating) / methylmalonate-semialdehyde dehydrogenase; MMSDH: methylmalonate-semialdehyde dehydrogenase
 
 0.995
bauC
Malonate-semialdehyde dehydrogenase (acetylating) / methylmalonate-semialdehyde dehydrogenase; Involved in the degradation of beta-alanine
 
 0.994
bkdB
The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity)
  
 
 0.971
DR97_1240
annotation not available
 0.960
AcsL
Amp-binding enzyme family protein; Belongs to the ATP-dependent AMP-binding enzyme family
  
 
  0.958
gabT
5-aminovalerate/4-aminobutyrate aminotransferase; Catalyzes the conversion of 5-aminovalerate to 5- oxopentanoate
   
 
 0.923
Pcd
Aldehyde dehydrogenase family protein; Belongs to the aldehyde dehydrogenase family
  
 0.922
PchA
Aldehyde dehydrogenase family protein; Belongs to the aldehyde dehydrogenase family
  
 0.920
BioA
Aminotransferase class-iii family protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
     
 0.900
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 287
Other names: ATCC 10145, ATCC 10145-U, Bacillus aeruginosus, Bacillus pyocyaneus, Bacterium aeruginosum, Bacterium pyocyaneum, CCEB 481, CCUG 28447, CCUG 29297, CCUG 551, CFBP 2466, CIP 100720, DSM 50071, IBCS 277, IFO 12689, JCM 5962, Micrococcus pyocyaneus, NBRC 12689, NCCB 76039, NCIB 8295, NCIMB 8295, NCTC 10332, NRRL B-771, P. aeruginosa, Pseudomonas polycolor, Pseudomonas pyocyanea, Pseudomonas sp. RV3, RH 815, VKM B-588, bacterium ASFP-37, bacterium ASFP-38, bacterium ASFP-45, bacterium ASFP-46, bacterium ASFP-48
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