node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DR97_4965 | rluC | DR97_4965 | DR97_4964 | Phosphoglycolate phosphatase; HAD-SF-IA-v1: HAD hydrolase, IA, variant 1 family protein | Ribosomal large subunit pseudouridine synthase c; Responsible for synthesis of pseudouridine from uracil at positions 955, 2504 and 2580 in 23S ribosomal RNA | 0.955 |
DR97_4965 | sppA | DR97_4965 | DR97_4966 | Phosphoglycolate phosphatase; HAD-SF-IA-v1: HAD hydrolase, IA, variant 1 family protein | sppA_dom: signal peptide peptidase SppA, 36K type | 0.915 |
cgtA | engA | DR97_1870 | DR97_4070 | Obg family gtpase cgta; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control | Ribosome-associated gtpase enga; GTPase that plays an essential role in the late steps of ribosome biogenesis | 0.922 |
cgtA | infB | DR97_1870 | DR97_2087 | Obg family gtpase cgta; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control | Translation initiation factor if-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex | 0.877 |
cgtA | lepA | DR97_1870 | DR97_1216 | Obg family gtpase cgta; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control | Gtp-binding protein lepa; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner | 0.954 |
cgtA | rluC | DR97_1870 | DR97_4964 | Obg family gtpase cgta; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control | Ribosomal large subunit pseudouridine synthase c; Responsible for synthesis of pseudouridine from uracil at positions 955, 2504 and 2580 in 23S ribosomal RNA | 0.745 |
cgtA | rplC | DR97_1870 | DR97_3648 | Obg family gtpase cgta; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control | Large subunit ribosomal protein l3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit | 0.837 |
cgtA | rplD | DR97_1870 | DR97_3649 | Obg family gtpase cgta; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control | Large subunit ribosomal protein l4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity). Forms part of the polypeptide exit tunnel | 0.837 |
engA | cgtA | DR97_4070 | DR97_1870 | Ribosome-associated gtpase enga; GTPase that plays an essential role in the late steps of ribosome biogenesis | Obg family gtpase cgta; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control | 0.922 |
engA | infB | DR97_4070 | DR97_2087 | Ribosome-associated gtpase enga; GTPase that plays an essential role in the late steps of ribosome biogenesis | Translation initiation factor if-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex | 0.741 |
engA | lepA | DR97_4070 | DR97_1216 | Ribosome-associated gtpase enga; GTPase that plays an essential role in the late steps of ribosome biogenesis | Gtp-binding protein lepa; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner | 0.791 |
engA | rluB | DR97_4070 | DR97_4757 | Ribosome-associated gtpase enga; GTPase that plays an essential role in the late steps of ribosome biogenesis | Pseudouridine synthase family protein; Responsible for synthesis of pseudouridine from uracil-2605 in 23S ribosomal RNA | 0.809 |
engA | rluC | DR97_4070 | DR97_4964 | Ribosome-associated gtpase enga; GTPase that plays an essential role in the late steps of ribosome biogenesis | Ribosomal large subunit pseudouridine synthase c; Responsible for synthesis of pseudouridine from uracil at positions 955, 2504 and 2580 in 23S ribosomal RNA | 0.771 |
engA | rplC | DR97_4070 | DR97_3648 | Ribosome-associated gtpase enga; GTPase that plays an essential role in the late steps of ribosome biogenesis | Large subunit ribosomal protein l3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit | 0.722 |
engA | rplD | DR97_4070 | DR97_3649 | Ribosome-associated gtpase enga; GTPase that plays an essential role in the late steps of ribosome biogenesis | Large subunit ribosomal protein l4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity). Forms part of the polypeptide exit tunnel | 0.852 |
infB | cgtA | DR97_2087 | DR97_1870 | Translation initiation factor if-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex | Obg family gtpase cgta; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control | 0.877 |
infB | engA | DR97_2087 | DR97_4070 | Translation initiation factor if-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex | Ribosome-associated gtpase enga; GTPase that plays an essential role in the late steps of ribosome biogenesis | 0.741 |
infB | lepA | DR97_2087 | DR97_1216 | Translation initiation factor if-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex | Gtp-binding protein lepa; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner | 0.668 |
infB | rluC | DR97_2087 | DR97_4964 | Translation initiation factor if-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex | Ribosomal large subunit pseudouridine synthase c; Responsible for synthesis of pseudouridine from uracil at positions 955, 2504 and 2580 in 23S ribosomal RNA | 0.811 |
infB | rplC | DR97_2087 | DR97_3648 | Translation initiation factor if-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex | Large subunit ribosomal protein l3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit | 0.989 |