node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
IscS | YrkI | DR97_5784 | DR97_941 | annotation not available | Trna 2-thiouridine synthesizing protein a; Belongs to the sulfur carrier protein TusA family | 0.888 |
IscS | fdx | DR97_5784 | DR97_4060 | annotation not available | Ferredoxin, 2fe-2s type, isc system; Ferredoxin are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions | 0.970 |
IscS | hscA | DR97_5784 | DR97_4059 | annotation not available | Fe-s protein assembly chaperone hsca; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB (By similarity) | 0.894 |
IscS | hscB | DR97_5784 | DR97_4058 | annotation not available | Fe-s protein assembly co-chaperone hscb; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA | 0.949 |
IscS | iscR | DR97_5784 | DR97_4054 | annotation not available | Rrf2 family transcriptional regulator, iron-sulfur cluster assembly transcription factor; Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins | 0.966 |
IscS | moeB | DR97_5784 | DR97_1972 | annotation not available | annotation not available | 0.946 |
IscS | nfuA | DR97_5784 | DR97_30 | annotation not available | Fe/s biogenesis protein nfua; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins | 0.878 |
IscS | nifU | DR97_5784 | DR97_4056 | annotation not available | Nitrogen fixation protein nifu and related proteins; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters | 0.999 |
IscS | thiI | DR97_5784 | DR97_2472 | annotation not available | Thiamine biosynthesis protein thii; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS | 0.991 |
IscS | tusA | DR97_5784 | DR97_371 | annotation not available | Trna 2-thiouridine synthesizing protein a; Sulfur carrier protein which probably makes part of a sulfur- relay system | 0.991 |
YrkI | IscS | DR97_941 | DR97_5784 | Trna 2-thiouridine synthesizing protein a; Belongs to the sulfur carrier protein TusA family | annotation not available | 0.888 |
YrkI | thiI | DR97_941 | DR97_2472 | Trna 2-thiouridine synthesizing protein a; Belongs to the sulfur carrier protein TusA family | Thiamine biosynthesis protein thii; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS | 0.519 |
YrkI | tusA | DR97_941 | DR97_371 | Trna 2-thiouridine synthesizing protein a; Belongs to the sulfur carrier protein TusA family | Trna 2-thiouridine synthesizing protein a; Sulfur carrier protein which probably makes part of a sulfur- relay system | 0.815 |
fdx | IscS | DR97_4060 | DR97_5784 | Ferredoxin, 2fe-2s type, isc system; Ferredoxin are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions | annotation not available | 0.970 |
fdx | hscA | DR97_4060 | DR97_4059 | Ferredoxin, 2fe-2s type, isc system; Ferredoxin are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions | Fe-s protein assembly chaperone hsca; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB (By similarity) | 0.999 |
fdx | hscB | DR97_4060 | DR97_4058 | Ferredoxin, 2fe-2s type, isc system; Ferredoxin are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions | Fe-s protein assembly co-chaperone hscb; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA | 0.998 |
fdx | iscR | DR97_4060 | DR97_4054 | Ferredoxin, 2fe-2s type, isc system; Ferredoxin are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions | Rrf2 family transcriptional regulator, iron-sulfur cluster assembly transcription factor; Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins | 0.967 |
fdx | nfuA | DR97_4060 | DR97_30 | Ferredoxin, 2fe-2s type, isc system; Ferredoxin are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions | Fe/s biogenesis protein nfua; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins | 0.662 |
fdx | nifU | DR97_4060 | DR97_4056 | Ferredoxin, 2fe-2s type, isc system; Ferredoxin are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions | Nitrogen fixation protein nifu and related proteins; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters | 0.997 |
fdx | tusA | DR97_4060 | DR97_371 | Ferredoxin, 2fe-2s type, isc system; Ferredoxin are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions | Trna 2-thiouridine synthesizing protein a; Sulfur carrier protein which probably makes part of a sulfur- relay system | 0.632 |