STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cynTCarbonate dehydratase; Belongs to the beta-class carbonic anhydrase family (220 aa)    
Predicted Functional Partners:
cynS
Cyanate hydratase; Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
 
 
 0.998
cynR
Bacterial regulatory helix-turn-helix , lysr family protein; Belongs to the LysR transcriptional regulatory family
 
   
 0.953
AccC
Acetyl-coa carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
  
 
 0.939
Pyc
Putative pyruvate carboxylase; Carbamoyl-phosphate synthase L chain, N-terminal domain protein
  
 
 0.921
oadA
oadA: oxaloacetate decarboxylase alpha subunit
    
  0.913
ppc
Phosphoenolpyruvate carboxylase family protein; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
    
 0.908
sstT
Dicarboxylate symporter family protein; Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
      
 0.866
mnmC
Trna 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
     
 0.856
YadF
Carbonic anhydrase family protein; Reversible hydration of carbon dioxide
  
  
0.839
DR97_3059
Carbonic anhydrase family protein; Reversible hydration of carbon dioxide
  
  
0.813
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 287
Other names: ATCC 10145, ATCC 10145-U, Bacillus aeruginosus, Bacillus pyocyaneus, Bacterium aeruginosum, Bacterium pyocyaneum, CCEB 481, CCUG 28447, CCUG 29297, CCUG 551, CFBP 2466, CIP 100720, DSM 50071, IBCS 277, IFO 12689, JCM 5962, Micrococcus pyocyaneus, NBRC 12689, NCCB 76039, NCIB 8295, NCIMB 8295, NCTC 10332, NRRL B-771, P. aeruginosa, Pseudomonas polycolor, Pseudomonas pyocyanea, Pseudomonas sp. RV3, RH 815, VKM B-588, bacterium ASFP-37, bacterium ASFP-38, bacterium ASFP-45, bacterium ASFP-46, bacterium ASFP-48
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