pslN protein (Pseudomonas aeruginosa) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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proteins of unknown 3D structure

filled nodes:
some 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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textmining

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Score

pslN

annotation not available (333 aa)

Predicted Functional Partners:

pslM

0.948

pslL

0.907

pslA

0.824

pslH

0.659

pslK

0.656

ligD

0.642

ku

0.629

pslD

0.628

gyrB

0.594

parE

0.594

Your Current Organism:

Pseudomonas aeruginosa

NCBI taxonomy Id: 287
Other names: ATCC 10145, ATCC 10145-U, Bacillus aeruginosus, Bacillus pyocyaneus, Bacterium aeruginosum, Bacterium pyocyaneum, CCEB 481, CCUG 28447, CCUG 29297, CCUG 551, CFBP 2466, CIP 100720, DSM 50071, IBCS 277, IFO 12689, JCM 5962, Micrococcus pyocyaneus, NBRC 12689, NCCB 76039, NCIB 8295, NCIMB 8295, NCTC 10332, NRRL B-771, P. aeruginosa, Pseudomonas aeruginosa, Pseudomonas polycolor, Pseudomonas pyocyanea, Pseudomonas sp. RV3, RH 815, VKM B-588, bacterium ASFP-37, bacterium ASFP-38, bacterium ASFP-45, bacterium ASFP-46, bacterium ASFP-48

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
gyrB	parE	DR97_2953	DR97_2320	DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	DNA topoisomerase 4 subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily	0.460
gyrB	pslN	DR97_2953	DR97_6306	DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	annotation not available	0.594
ku	ligD	DR97_6276	DR97_6291	Non-homologous end joining protein Ku; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5’- and 3’- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD	ATP-dependent DNA ligase; ligD_pol- DNA polymerase LigD, polymerase domain	0.982
ku	pslN	DR97_6276	DR97_6306	Non-homologous end joining protein Ku; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5’- and 3’- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD	annotation not available	0.629
ligD	ku	DR97_6291	DR97_6276	ATP-dependent DNA ligase; ligD_pol- DNA polymerase LigD, polymerase domain	Non-homologous end joining protein Ku; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5’- and 3’- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD	0.982
ligD	pslN	DR97_6291	DR97_6306	ATP-dependent DNA ligase; ligD_pol- DNA polymerase LigD, polymerase domain	annotation not available	0.642
parE	gyrB	DR97_2320	DR97_2953	DNA topoisomerase 4 subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily	DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	0.460
parE	pslN	DR97_2320	DR97_6306	DNA topoisomerase 4 subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily	annotation not available	0.594
pslA	pslD	DR97_6320	DR97_6317	Putative glycosyl transferase; wcaJ_sugtrans- undecaprenyl-phosphate glucose phosphotransferase	annotation not available	0.996
pslA	pslH	DR97_6320	DR97_6313	Putative glycosyl transferase; wcaJ_sugtrans- undecaprenyl-phosphate glucose phosphotransferase	annotation not available	0.957
pslA	pslK	DR97_6320	DR97_6310	Putative glycosyl transferase; wcaJ_sugtrans- undecaprenyl-phosphate glucose phosphotransferase	annotation not available	0.932
pslA	pslL	DR97_6320	DR97_6308	Putative glycosyl transferase; wcaJ_sugtrans- undecaprenyl-phosphate glucose phosphotransferase	annotation not available	0.926
pslA	pslM	DR97_6320	DR97_6307	Putative glycosyl transferase; wcaJ_sugtrans- undecaprenyl-phosphate glucose phosphotransferase	annotation not available	0.810
pslA	pslN	DR97_6320	DR97_6306	Putative glycosyl transferase; wcaJ_sugtrans- undecaprenyl-phosphate glucose phosphotransferase	annotation not available	0.824
pslD	pslA	DR97_6317	DR97_6320	annotation not available	Putative glycosyl transferase; wcaJ_sugtrans- undecaprenyl-phosphate glucose phosphotransferase	0.996
pslD	pslH	DR97_6317	DR97_6313	annotation not available	annotation not available	0.990
pslD	pslK	DR97_6317	DR97_6310	annotation not available	annotation not available	0.988
pslD	pslL	DR97_6317	DR97_6308	annotation not available	annotation not available	0.943
pslD	pslN	DR97_6317	DR97_6306	annotation not available	annotation not available	0.628
pslH	pslA	DR97_6313	DR97_6320	annotation not available	Putative glycosyl transferase; wcaJ_sugtrans- undecaprenyl-phosphate glucose phosphotransferase	0.957

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