fabI protein (Pseudomonas aeruginosa) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

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experimentally determined

Predicted Interactions

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protein homology

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Score

fabI

annotation not available (265 aa)

Predicted Functional Partners:

fabF1

0.994

fabB

0.994

fabZ

0.993

fabF3

0.991

fabA

0.990

acpP_1

0.987

fabV

0.972

DR97_6

0.949

acpP_3

0.937

DR97_3055

0.931

Your Current Organism:

Pseudomonas aeruginosa

NCBI taxonomy Id: 287
Other names: ATCC 10145, ATCC 10145-U, Bacillus aeruginosus, Bacillus pyocyaneus, Bacterium aeruginosum, Bacterium pyocyaneum, CCEB 481, CCUG 28447, CCUG 29297, CCUG 551, CFBP 2466, CIP 100720, DSM 50071, IBCS 277, IFO 12689, JCM 5962, Micrococcus pyocyaneus, NBRC 12689, NCCB 76039, NCIB 8295, NCIMB 8295, NCTC 10332, NRRL B-771, P. aeruginosa, Pseudomonas aeruginosa, Pseudomonas polycolor, Pseudomonas pyocyanea, Pseudomonas sp. RV3, RH 815, VKM B-588, bacterium ASFP-37, bacterium ASFP-38, bacterium ASFP-45, bacterium ASFP-46, bacterium ASFP-48

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DR97_3055	DR97_6	DR97_3055	DR97_6	Beta-ketoacyl synthase, N-terminal domain protein	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis	0.518
DR97_3055	acpP_1	DR97_3055	DR97_4973	Beta-ketoacyl synthase, N-terminal domain protein	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis	0.550
DR97_3055	acpP_3	DR97_3055	DR97_4593	Beta-ketoacyl synthase, N-terminal domain protein	annotation not available	0.518
DR97_3055	fabA	DR97_3055	DR97_279	Beta-ketoacyl synthase, N-terminal domain protein	3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase; Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16-0, being most active on intermediate chain length	0.519
DR97_3055	fabB	DR97_3055	DR97_280	Beta-ketoacyl synthase, N-terminal domain protein	3-oxoacyl-[acyl-carrier-protein] synthase 1; Thiolase, N-terminal domain protein; Belongs to the beta-ketoacyl-ACP synthases family	0.800
DR97_3055	fabF1	DR97_3055	DR97_4974	Beta-ketoacyl synthase, N-terminal domain protein	3-oxoacyl-[acyl-carrier-protein] synthase 2; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	0.900
DR97_3055	fabF3	DR97_3055	DR97_425	Beta-ketoacyl synthase, N-terminal domain protein	3-oxoacyl-[acyl-carrier-protein] synthase 2; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	0.900
DR97_3055	fabI	DR97_3055	DR97_73	Beta-ketoacyl synthase, N-terminal domain protein	annotation not available	0.931
DR97_3055	fabV	DR97_3055	DR97_4989	Beta-ketoacyl synthase, N-terminal domain protein	Enoyl-[acyl-carrier-protein] reductase [NADH]; Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP); Belongs to the TER reductase family	0.912
DR97_3055	fabZ	DR97_3055	DR97_4294	Beta-ketoacyl synthase, N-terminal domain protein	3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	0.519
DR97_6	DR97_3055	DR97_6	DR97_3055	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis	Beta-ketoacyl synthase, N-terminal domain protein	0.518
DR97_6	fabA	DR97_6	DR97_279	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis	3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase; Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16-0, being most active on intermediate chain length	0.927
DR97_6	fabB	DR97_6	DR97_280	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis	3-oxoacyl-[acyl-carrier-protein] synthase 1; Thiolase, N-terminal domain protein; Belongs to the beta-ketoacyl-ACP synthases family	0.933
DR97_6	fabF1	DR97_6	DR97_4974	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis	3-oxoacyl-[acyl-carrier-protein] synthase 2; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	0.924
DR97_6	fabF3	DR97_6	DR97_425	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis	3-oxoacyl-[acyl-carrier-protein] synthase 2; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	0.911
DR97_6	fabI	DR97_6	DR97_73	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis	annotation not available	0.949
DR97_6	fabV	DR97_6	DR97_4989	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis	Enoyl-[acyl-carrier-protein] reductase [NADH]; Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP); Belongs to the TER reductase family	0.793
DR97_6	fabZ	DR97_6	DR97_4294	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis	3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	0.949
acpP_1	DR97_3055	DR97_4973	DR97_3055	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis	Beta-ketoacyl synthase, N-terminal domain protein	0.550
acpP_1	fabA	DR97_4973	DR97_279	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis	3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase; Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16-0, being most active on intermediate chain length	0.992

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