node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SIT74348.1 | SIT76691.1 | SAMN05421665_0034 | SAMN05421665_0424 | Phosphopantetheine attachment site. | 5-aminolevulinate synthase. | 0.786 |
SIT74348.1 | SIT78362.1 | SAMN05421665_0034 | SAMN05421665_0760 | Phosphopantetheine attachment site. | Porphobilinogen synthase; Belongs to the ALAD family. | 0.565 |
SIT74348.1 | SIT80110.1 | SAMN05421665_0034 | SAMN05421665_1055 | Phosphopantetheine attachment site. | [acyl-carrier-protein] S-malonyltransferase. | 0.998 |
SIT74348.1 | SIT82422.1 | SAMN05421665_0034 | SAMN05421665_1457 | Phosphopantetheine attachment site. | L-2,4-diaminobutyrate transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.844 |
SIT74348.1 | SIT83899.1 | SAMN05421665_0034 | SAMN05421665_1748 | Phosphopantetheine attachment site. | Signal transduction histidine kinase. | 0.961 |
SIT74348.1 | SIT87282.1 | SAMN05421665_0034 | SAMN05421665_2333 | Phosphopantetheine attachment site. | Acyl transferase domain-containing protein. | 0.999 |
SIT74348.1 | SIT90152.1 | SAMN05421665_0034 | SAMN05421665_3005 | Phosphopantetheine attachment site. | Putrescine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.844 |
SIT74348.1 | gcvP | SAMN05421665_0034 | SAMN05421665_0684 | Phosphopantetheine attachment site. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.507 |
SIT74348.1 | glyA | SAMN05421665_0034 | SAMN05421665_0108 | Phosphopantetheine attachment site. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.540 |
SIT76691.1 | SIT74348.1 | SAMN05421665_0424 | SAMN05421665_0034 | 5-aminolevulinate synthase. | Phosphopantetheine attachment site. | 0.786 |
SIT76691.1 | SIT78362.1 | SAMN05421665_0424 | SAMN05421665_0760 | 5-aminolevulinate synthase. | Porphobilinogen synthase; Belongs to the ALAD family. | 0.837 |
SIT76691.1 | SIT80110.1 | SAMN05421665_0424 | SAMN05421665_1055 | 5-aminolevulinate synthase. | [acyl-carrier-protein] S-malonyltransferase. | 0.721 |
SIT76691.1 | SIT82422.1 | SAMN05421665_0424 | SAMN05421665_1457 | 5-aminolevulinate synthase. | L-2,4-diaminobutyrate transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.699 |
SIT76691.1 | SIT83899.1 | SAMN05421665_0424 | SAMN05421665_1748 | 5-aminolevulinate synthase. | Signal transduction histidine kinase. | 0.872 |
SIT76691.1 | SIT85494.1 | SAMN05421665_0424 | SAMN05421665_2073 | 5-aminolevulinate synthase. | L-iditol 2-dehydrogenase. | 0.786 |
SIT76691.1 | SIT87282.1 | SAMN05421665_0424 | SAMN05421665_2333 | 5-aminolevulinate synthase. | Acyl transferase domain-containing protein. | 0.855 |
SIT76691.1 | SIT90152.1 | SAMN05421665_0424 | SAMN05421665_3005 | 5-aminolevulinate synthase. | Putrescine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.701 |
SIT76691.1 | gcvP | SAMN05421665_0424 | SAMN05421665_0684 | 5-aminolevulinate synthase. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.846 |
SIT76691.1 | glyA | SAMN05421665_0424 | SAMN05421665_0108 | 5-aminolevulinate synthase. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.772 |
SIT78362.1 | SIT74348.1 | SAMN05421665_0760 | SAMN05421665_0034 | Porphobilinogen synthase; Belongs to the ALAD family. | Phosphopantetheine attachment site. | 0.565 |