STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SIT77272.12-Methylisocitrate lyase, PEP mutase family. (269 aa)    
Predicted Functional Partners:
SIT77014.1
Citrate synthase; Belongs to the citrate synthase family.
  
 0.947
SIT77276.1
DNA-O6-methylguanine--protein-cysteine S-methyltransferase /Transcriptional regulator Ada.
       0.844
glcB
Malate synthase; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.
   
 
 0.833
SIT74829.1
Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+).
    
 0.780
SIT88149.1
Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+).
    
 0.780
SIT79953.1
Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
     
 0.772
SIT80311.1
Aconitase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
  
 0.750
mdh
Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
  
 0.708
SIT77282.1
Arginine:pyruvate transaminase.
  
 
 0.694
SIT81597.1
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
   
 0.646
Your Current Organism:
Yoonia rosea
NCBI taxonomy Id: 287098
Other names: CIP 107851, DSM 29591, KMM 6003, LMG 22534, LMG:22534, Loktanella rosea, Loktanella rosea Ivanova et al. 2005, Y. rosea, strain Fg36
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