STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SIT85608.1beta-methylmalyl-CoA/L-malyl-CoA lyase; Belongs to the HpcH/HpaI aldolase family. (318 aa)    
Predicted Functional Partners:
SIT85388.1
L-erythro-3-methylmalyl-CoA dehydratase.
 
 
 0.944
SIT88767.1
Ribulose-5-phosphate 4-epimerase/Fuculose-1-phosphate aldolase.
   
    0.815
mdh
Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
  
 
 0.783
SIT87562.1
Crotonobetainyl-CoA:carnitine CoA-transferase CaiB; Belongs to the CoA-transferase III family.
 
 0.783
glcB
Malate synthase; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.
    
 0.770
SIT85128.1
Glyoxylate reductase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
 
  
 0.770
sucC
succinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
    
 0.765
SIT74829.1
Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+).
  
 
 0.761
SIT88149.1
Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+).
  
 
 0.761
sucD
succinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
 
 0.759
Your Current Organism:
Yoonia rosea
NCBI taxonomy Id: 287098
Other names: CIP 107851, DSM 29591, KMM 6003, LMG 22534, LMG:22534, Loktanella rosea, Loktanella rosea Ivanova et al. 2005, Y. rosea, strain Fg36
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