Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
LOC107093437Sphingomyelin phosphodiesterase 4. (648 aa)    
Predicted Functional Partners:
smpd3
Sphingomyelin phosphodiesterase 3, neutral.
      
 0.885
smpd2
Sphingomyelin phosphodiesterase 2b, neutral membrane (neutral sphingomyelinase).
      
 0.855
ncln
Nicalin.
   
  
 0.780
ddx11
DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11.
   
  
 0.757
rrp7a
Ribosomal RNA processing 7 homolog A.
      
 0.756
ndc1
NDC1 transmembrane nucleoporin.
   
  
 0.718
TMEM43
Uncharacterized protein.
      
 0.685
LOC107102397
Sphingomyelin phosphodiesterase 5.
      
 0.679
smpd1
Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide.
      
 0.662
LOC107095277
Uncharacterized protein.
   
  
 0.627
Your Current Organism:
Cyprinodon variegatus
NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow
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