LOC107099231 protein (Cyprinodon variegatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

LOC107099231

Uncharacterized protein. (387 aa)

Predicted Functional Partners:

tp53

0.651

DCAF7

0.581

ENSCVAP00000004123

0.581

dcaf7

0.581

ENSCVAP00000011755

0.506

Atm

0.506

plk3

0.493

plk2

0.493

PLK1

0.493

Pin1

0.492

Your Current Organism:

Cyprinodon variegatus

NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Atm	ENSCVAP00000011755	ENSCVAP00000011758	ENSCVAP00000011755	Uncharacterized protein.	TAN domain-containing protein.	0.922
Atm	LOC107099231	ENSCVAP00000011758	ENSCVAP00000000962	Uncharacterized protein.	Uncharacterized protein.	0.506
Atm	tp53	ENSCVAP00000011758	ENSCVAP00000022398	Uncharacterized protein.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.994
DCAF7	LOC107099231	ENSCVAP00000004103	ENSCVAP00000000962	DDB1 and CUL4 associated factor 7.	Uncharacterized protein.	0.581
ENSCVAP00000004123	LOC107099231	ENSCVAP00000004123	ENSCVAP00000000962	Uncharacterized protein.	Uncharacterized protein.	0.581
ENSCVAP00000011755	Atm	ENSCVAP00000011755	ENSCVAP00000011758	TAN domain-containing protein.	Uncharacterized protein.	0.922
ENSCVAP00000011755	LOC107099231	ENSCVAP00000011755	ENSCVAP00000000962	TAN domain-containing protein.	Uncharacterized protein.	0.506
ENSCVAP00000011755	tp53	ENSCVAP00000011755	ENSCVAP00000022398	TAN domain-containing protein.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.947
LOC107099231	Atm	ENSCVAP00000000962	ENSCVAP00000011758	Uncharacterized protein.	Uncharacterized protein.	0.506
LOC107099231	DCAF7	ENSCVAP00000000962	ENSCVAP00000004103	Uncharacterized protein.	DDB1 and CUL4 associated factor 7.	0.581
LOC107099231	ENSCVAP00000004123	ENSCVAP00000000962	ENSCVAP00000004123	Uncharacterized protein.	Uncharacterized protein.	0.581
LOC107099231	ENSCVAP00000011755	ENSCVAP00000000962	ENSCVAP00000011755	Uncharacterized protein.	TAN domain-containing protein.	0.506
LOC107099231	PLK1	ENSCVAP00000000962	ENSCVAP00000030252	Uncharacterized protein.	Serine/threonine-protein kinase PLK.	0.493
LOC107099231	Pin1	ENSCVAP00000000962	ENSCVAP00000026915	Uncharacterized protein.	Peptidyl-prolyl cis-trans isomerase.	0.492
LOC107099231	dcaf7	ENSCVAP00000000962	ENSCVAP00000009609	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.581
LOC107099231	plk2	ENSCVAP00000000962	ENSCVAP00000025968	Uncharacterized protein.	Serine/threonine-protein kinase PLK.	0.493
LOC107099231	plk3	ENSCVAP00000000962	ENSCVAP00000007698	Uncharacterized protein.	Serine/threonine-protein kinase PLK.	0.493
LOC107099231	tp53	ENSCVAP00000000962	ENSCVAP00000022398	Uncharacterized protein.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.651
PLK1	LOC107099231	ENSCVAP00000030252	ENSCVAP00000000962	Serine/threonine-protein kinase PLK.	Uncharacterized protein.	0.493
PLK1	tp53	ENSCVAP00000030252	ENSCVAP00000022398	Serine/threonine-protein kinase PLK.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.721