Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
hhipHedgehog interacting protein. (696 aa)    
Predicted Functional Partners:
shh
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
    
 0.991
ihh
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
    
 0.988
LOC107103858
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
    
 0.988
LOC107086754
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
    
 0.982
LOC107091888
HH_signal domain-containing protein.
    
 0.863
dym
Dymeclin.
      
 0.797
nrp1
Neuropilin; Belongs to the neuropilin family.
    
 
 0.761
usp38
Ubiquitin specific peptidase 38; Belongs to the peptidase C19 family.
      
 0.749
ptch2
Patched 2.
    
 
 0.734
bckdhb
Branched chain keto acid dehydrogenase E1 subunit beta.
      
 0.733
Your Current Organism:
Cyprinodon variegatus
NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow
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