Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
LOC107105047Pellino E3 ubiquitin protein ligase 1b. (426 aa)    
Predicted Functional Partners:
irak4
Interleukin-1 receptor-associated kinase 4.
    
 0.870
traf6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.850
irak1
Interleukin-1 receptor-associated kinase 1.
    
 0.817
LOC107090723
Ubiquitin-conjugating enzyme E2 variant 1.
    
 0.707
LOC107094607
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.680
LOC107103559
Ubiquitin-conjugating enzyme E2Nb; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.680
ripk1
Receptor (TNFRSF)-interacting serine-threonine kinase 1, like.
    
 0.641
ENSCVAP00000011893
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
    
 0.564
LOC107097523
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
    
 0.564
ENSCVAP00000029008
Ubiquitin-conjugating enzyme E2 variant 2.
    
 0.560
Your Current Organism:
Cyprinodon variegatus
NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow
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