STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC107095805Furin (paired basic amino acid cleaving enzyme) a; Belongs to the peptidase S8 family. (810 aa)    
Predicted Functional Partners:
LOC107093919
Matrix metallopeptidase 11.
    
 0.787
LOC107103644
Matrix metallopeptidase 11a.
    
 0.736
gramd4
GRAM domain containing 4a.
    
 0.689
GRAMD4
GRAM domain containing 4.
    
 0.689
proc
Uncharacterized protein.
  
 
 0.679
lig4
DNA ligase.
   
  
 0.677
LOC107103699
Transforming growth factor beta; Belongs to the TGF-beta family.
    
 0.668
emc3
ER membrane protein complex subunit 3; Belongs to the EMC3 family.
   
  
 0.666
edar
Ectodysplasin A receptor.
      
 0.665
f2
Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.
  
 
 0.657
Your Current Organism:
Cyprinodon variegatus
NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.