txndc5 protein (Cyprinodon variegatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

txndc5

Thioredoxin domain containing 5; Belongs to the protein disulfide isomerase family. (411 aa)

Predicted Functional Partners:

ero1a

0.965

ero1b

0.965

prdx4

0.956

hspa5

0.883

hsp90b1

0.746

gak

0.722

LOC107080670

0.700

LOC107101296

0.700

prdx3

0.683

prdx2

0.683

Your Current Organism:

Cyprinodon variegatus

NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC107080670	LOC107101296	ENSCVAP00000014845	ENSCVAP00000019668	Calreticulin.	Calreticulin.	0.914
LOC107080670	hsp90b1	ENSCVAP00000014845	ENSCVAP00000007180	Calreticulin.	Heat shock protein 90, beta (grp94), member 1.	0.974
LOC107080670	hspa5	ENSCVAP00000014845	ENSCVAP00000029709	Calreticulin.	Heat shock protein 5; Belongs to the heat shock protein 70 family.	0.926
LOC107080670	txndc5	ENSCVAP00000014845	ENSCVAP00000001280	Calreticulin.	Thioredoxin domain containing 5; Belongs to the protein disulfide isomerase family.	0.700
LOC107101296	LOC107080670	ENSCVAP00000019668	ENSCVAP00000014845	Calreticulin.	Calreticulin.	0.914
LOC107101296	hsp90b1	ENSCVAP00000019668	ENSCVAP00000007180	Calreticulin.	Heat shock protein 90, beta (grp94), member 1.	0.974
LOC107101296	hspa5	ENSCVAP00000019668	ENSCVAP00000029709	Calreticulin.	Heat shock protein 5; Belongs to the heat shock protein 70 family.	0.926
LOC107101296	txndc5	ENSCVAP00000019668	ENSCVAP00000001280	Calreticulin.	Thioredoxin domain containing 5; Belongs to the protein disulfide isomerase family.	0.700
ero1a	ero1b	ENSCVAP00000023098	ENSCVAP00000029796	Endoplasmic reticulum oxidoreductase alpha.	Endoplasmic reticulum oxidoreductase beta.	0.902
ero1a	hspa5	ENSCVAP00000023098	ENSCVAP00000029709	Endoplasmic reticulum oxidoreductase alpha.	Heat shock protein 5; Belongs to the heat shock protein 70 family.	0.719
ero1a	txndc5	ENSCVAP00000023098	ENSCVAP00000001280	Endoplasmic reticulum oxidoreductase alpha.	Thioredoxin domain containing 5; Belongs to the protein disulfide isomerase family.	0.965
ero1b	ero1a	ENSCVAP00000029796	ENSCVAP00000023098	Endoplasmic reticulum oxidoreductase beta.	Endoplasmic reticulum oxidoreductase alpha.	0.902
ero1b	hspa5	ENSCVAP00000029796	ENSCVAP00000029709	Endoplasmic reticulum oxidoreductase beta.	Heat shock protein 5; Belongs to the heat shock protein 70 family.	0.719
ero1b	txndc5	ENSCVAP00000029796	ENSCVAP00000001280	Endoplasmic reticulum oxidoreductase beta.	Thioredoxin domain containing 5; Belongs to the protein disulfide isomerase family.	0.965
gak	hspa5	ENSCVAP00000026432	ENSCVAP00000029709	Cyclin G associated kinase.	Heat shock protein 5; Belongs to the heat shock protein 70 family.	0.864
gak	txndc5	ENSCVAP00000026432	ENSCVAP00000001280	Cyclin G associated kinase.	Thioredoxin domain containing 5; Belongs to the protein disulfide isomerase family.	0.722
hsp90b1	LOC107080670	ENSCVAP00000007180	ENSCVAP00000014845	Heat shock protein 90, beta (grp94), member 1.	Calreticulin.	0.974
hsp90b1	LOC107101296	ENSCVAP00000007180	ENSCVAP00000019668	Heat shock protein 90, beta (grp94), member 1.	Calreticulin.	0.974
hsp90b1	hspa5	ENSCVAP00000007180	ENSCVAP00000029709	Heat shock protein 90, beta (grp94), member 1.	Heat shock protein 5; Belongs to the heat shock protein 70 family.	0.988
hsp90b1	txndc5	ENSCVAP00000007180	ENSCVAP00000001280	Heat shock protein 90, beta (grp94), member 1.	Thioredoxin domain containing 5; Belongs to the protein disulfide isomerase family.	0.746