Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
txndc5Thioredoxin domain containing 5; Belongs to the protein disulfide isomerase family. (411 aa)    
Predicted Functional Partners:
ero1a
Endoplasmic reticulum oxidoreductase alpha.
   
 0.957
ero1b
Endoplasmic reticulum oxidoreductase beta.
   
 0.957
prdx4
Peroxiredoxin 4.
  
 0.948
bloc1s1
Biogenesis of lysosomal organelles complex-1, subunit 1.
     
 0.941
hspa5
Heat shock protein 5; Belongs to the heat shock protein 70 family.
   
 0.938
bloc1s6
Biogenesis of lysosome-related organelles complex 1 subunit 6; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May play a role in intracellular vesicle trafficking, particular [...]
   
 
  0.802
hsp90b1
Heat shock protein 90, beta (grp94), member 1.
   
 0.785
gmppb
GDP-mannose pyrophosphorylase B.
  
 
 0.734
LOC107080670
Calreticulin.
   
 0.715
LOC107101296
Calreticulin.
   
 0.715
Your Current Organism:
Cyprinodon variegatus
NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow
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