STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
f5Coagulation factor V; Belongs to the multicopper oxidase family. (1758 aa)    
Predicted Functional Partners:
f2
Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.
    
 0.894
proc
Uncharacterized protein.
    
 0.730
pros1
Protein S.
   
 0.702
mcfd2
Multiple coagulation factor deficiency 2.
     
 0.693
lman1
Lectin, mannose-binding, 1.
    
 0.657
serpine2
Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2; Belongs to the serpin family.
    
 0.647
LOC107086236
Hemoglobin, alpha embryonic 5; Belongs to the globin family.
      
 0.643
serpinc1
Serpin peptidase inhibitor, clade C (antithrombin), member 1; Belongs to the serpin family.
   
 0.631
scfd1
Sec1 family domain containing 1; Belongs to the STXBP/unc-18/SEC1 family.
     
 0.606
ctsc
Cathepsin C; Belongs to the peptidase C1 family.
   
 
 0.605
Your Current Organism:
Cyprinodon variegatus
NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.