Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
rab8aRAB8A, member RAS oncogene family. (206 aa)    
Predicted Functional Partners:
wdr41
WD repeat domain 41.
     
 0.938
c9orf72
Zgc:100846.
    
 0.936
micall2
Mical-like 2a.
    
 0.935
LOC107097038
Uncharacterized protein.
    
 0.935
LOC107093106
Smith-Magenis syndrome chromosome region, candidate 8a.
    
 0.919
smcr8
UDENN FLCN/SMCR8-type domain-containing protein.
    
 0.919
sqstm1
Sequestosome 1.
    
 0.912
LOC107102129
Multiple EGF-like-domains 8.
  
  
 
0.901
LOC107085938
RAB8A, member RAS oncogene family.
  
  
 
0.900
exoc5
Exocyst complex component 5.
   
 0.759
Your Current Organism:
Cyprinodon variegatus
NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow
Server load: low (12%) [HD]