Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
hdac11Histone deacetylase 11. (348 aa)    
Predicted Functional Partners:
rsrc1
Uncharacterized protein.
    
   0.774
dicer1
Dicer 1, ribonuclease type III; Belongs to the helicase family. Dicer subfamily.
    
 
 0.692
arid4b
Translocase of outer mitochondrial membrane 20.
    
 0.690
Arid4a
Tudor domain-containing protein.
    
 0.690
sirt1
Sirtuin 1.
    
 0.661
ENSCVAP00000002779
GPS2_interact domain-containing protein.
    
 0.653
Ncor1
Uncharacterized protein.
    
 0.653
ncor2
Nuclear receptor corepressor 2.
    
 0.653
rbbp4
Retinoblastoma binding protein 4.
   
 0.623
nup35
Nucleoporin NUP53; Functions as a component of the nuclear pore complex (NPC). Belongs to the Nup35 family.
     
 0.621
Your Current Organism:
Cyprinodon variegatus
NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow
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