Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
tmem97Transmembrane protein 97; Intracellular orphan receptor that binds numerous drugs and which is highly expressed in various proliferating cells. Corresponds to the sigma-2 receptor, which is thought to play important role in regulating cell survival, morphology and differentiation. May play a role as a regulator of cellular cholesterol homeostasis. May function as sterol isomerase. May alter the activity of some cytochrome P450 proteins. (177 aa)    
Predicted Functional Partners:
pgrmc1
Progesterone receptor membrane component 1; Belongs to the cytochrome b5 family.
     
 0.918
pgrmc2
Progesterone receptor membrane component 2; Belongs to the cytochrome b5 family.
     
 0.845
sigmar1
Sigma non-opioid intracellular receptor 1.
   
  
 0.769
smim4
Small integral membrane protein 4.
      
 0.716
tmem94
Transmembrane protein 94.
      
 0.681
glt8d1
Glycosyltransferase 8 domain containing 1.
      
 0.658
ldah
Lipid droplet associated hydrolase.
   
  
 0.614
bsdc1
BSD domain containing 1.
      
 0.611
ENSCVAP00000017549
ATPase_AAA_core domain-containing protein.
    
 0.591
LOC107083670
Urea transporter; Belongs to the urea transporter family.
    
 
 0.552
Your Current Organism:
Cyprinodon variegatus
NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow
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