Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
rnf139Ring finger protein 139. (698 aa)    
Predicted Functional Partners:
LOC107100870
Histocompatibility (minor) 13.
   
 
 0.852
LOC107081332
Uncharacterized protein.
   
 
 0.852
os9
OS9 endoplasmic reticulum lectin.
   
 0.749
erlec1
Endoplasmic reticulum lectin 1.
   
 0.749
ube2g2
Ubiquitin-conjugating enzyme E2G 2 (UBC7 homolog, yeast); Belongs to the ubiquitin-conjugating enzyme family.
    
 
 0.749
ngly1
N-glycanase 1.
   
 0.681
sel1l
SEL1L adaptor subunit of ERAD E3 ubiquitin ligase.
    
 0.678
INSIG1
Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family.
    
 
 0.677
insig2
Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family.
    
 
 0.677
LOC107103646
Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.
    
 0.670
Your Current Organism:
Cyprinodon variegatus
NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow
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