Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
dmc1DNA meiotic recombinase 1; Belongs to the RecA family. (261 aa)    
Predicted Functional Partners:
rad51
DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...]
   
 0.984
ENSCVAP00000010146
Tower domain-containing protein.
   
 0.983
spo11
SPO11 initiator of meiotic double stranded breaks.
   
 0.971
XRCC3
X-ray repair complementing defective repair in Chinese hamster cells 3.
  
 0.961
trip13
Thyroid hormone receptor interactor 13; Belongs to the AAA ATPase family.
  
 0.924
ENSCVAP00000027264
Zebrafish testis-expressed 38.
   
 
 0.906
fancm
Uncharacterized protein.
   
 0.902
ENSCVAP00000015397
Uncharacterized protein.
   
 0.875
rad1
RAD1 homolog (S. pombe).
   
 0.875
rad51d
RAD51 paralog D.
   
 0.874
Your Current Organism:
Cyprinodon variegatus
NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow
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