Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
LOC107087244Nuclear receptor subfamily 2, group F, member 2. (424 aa)    
Predicted Functional Partners:
yap1
Yes-associated protein 1.
   
 
 0.842
SOX18
SRY-box transcription factor 18.
   
 
 0.837
LOC107092835
Axin 2 (conductin, axil).
     
 0.788
AXIN2
Axin 2.
     
 0.788
LOC107104327
Uncharacterized protein.
    
 
 0.737
irx3
Iroquois homeobox 3a.
    
 
 0.725
med1
Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
    
  0.628
LOC107093502
Eph receptor B4a.
    
 0.626
LOC107083213
Link domain-containing protein.
   
 0.623
LOC107103885
Vascular endothelial growth factor c; Belongs to the PDGF/VEGF growth factor family.
      
 0.607
Your Current Organism:
Cyprinodon variegatus
NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow
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