STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC107092854Phosphoinositide-3-kinase, regulatory subunit 1 (alpha). (728 aa)    
Predicted Functional Partners:
LOC107089396
PH domain-containing protein.
    
 0.971
LOC107087768
Si:ch73-335l21.1.
    
 0.960
pdpk1
3-phosphoinositide dependent protein kinase 1b.
     
 0.959
kdr
Kinase insert domain receptor (a type III receptor tyrosine kinase); Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
    
 0.956
LOC107102648
Inositol polyphosphate phosphatase-like 1b.
    
 0.945
erbb3
Protein kinase domain-containing protein.
    
 0.944
erbb2
Receptor protein-tyrosine kinase.
    
 0.944
LOC107092166
Erb-b2 receptor tyrosine kinase 3b.
    
 0.944
LOC107092536
Rac family small GTPase 1b.
    
  0.940
hras
HRas proto-oncogene, GTPase a.
    
 0.938
Your Current Organism:
Cyprinodon variegatus
NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.