STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC107095780Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (217 aa)    
Predicted Functional Partners:
cdc6
Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family.
   
 0.786
orc2
Origin recognition complex, subunit 2.
   
 0.767
ENSCVAP00000022427
Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.
  
  
  0.731
ENSCVAP00000000165
Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.
  
  
  0.725
LOC107103641
Uncharacterized protein.
     
 0.725
LOC107084763
Claudin i.
  
  
  0.722
ENSCVAP00000010828
Claudin 23a.
     
0.717
atr
ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.
    
 0.713
ENSCVAP00000031104
Tight junction protein 3; Belongs to the MAGUK family.
    
 0.705
mcm3
DNA helicase; Belongs to the MCM family.
   
 0.702
Your Current Organism:
Cyprinodon variegatus
NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.