Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
wrap73WD repeat containing, antisense to TP73. (452 aa)    
Predicted Functional Partners:
cep135
Centrosomal protein 135.
    
 
 0.920
obi1
ORC ubiquitin ligase 1.
    
   0.885
tbc1d31
TBC1 domain family, member 31.
    
 
 0.728
gpr153
G protein-coupled receptor 153.
    
 
 0.716
Nat10
DUF1726 domain-containing protein.
      
 0.710
ENSCVAP00000014798
DEAD (Asp-Glu-Ala-Asp) box polypeptide 51; Belongs to the DEAD box helicase family.
      
 0.708
suclg2
Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
      
 0.696
acot7
Acyl-CoA thioesterase 7.
      
 0.681
kif11
Kinesin family member 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
    
 
 0.679
LOC107086674
Rho guanine nucleotide exchange factor (GEF) 16.
      
 0.674
Your Current Organism:
Cyprinodon variegatus
NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow
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