Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC107104990A-Raf proto-oncogene, serine/threonine kinase. (584 aa)    
Predicted Functional Partners:
map2k1
Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily.
   
0.982
map2k2
Mitogen-activated protein kinase kinase 2a; Belongs to the protein kinase superfamily.
   
0.982
LOC107095138
Zgc:55558.
    
 0.980
KRAS
V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog.
    
 0.980
hras
HRas proto-oncogene, GTPase a.
    
 0.980
mras
Muscle RAS oncogene homolog.
    
 0.976
LOC107103920
RAS related.
    
 0.974
rras2
RAS related 2.
    
 0.974
raf1
Raf-1 proto-oncogene, serine/threonine kinase a.
  
  
 
0.908
braf
B-Raf proto-oncogene, serine/threonine kinase.
  
  
 
0.908
Your Current Organism:
Cyprinodon variegatus
NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow
Server load: low (40%) [HD]