Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
igf1rTyrosine-protein kinase receptor. (1416 aa)    
Predicted Functional Partners:
igf1
Insulin-like growth factor 1.
    
 0.988
ins
Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
    
 0.987
ENSCVAP00000030679
IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
    
 0.987
LOC107087768
Si:ch73-335l21.1.
    
 0.978
LOC107091522
Insulin receptor substrate 4a.
    
 0.978
LOC107086777
Insulin receptor substrate 2a.
    
 0.978
irs2
Insulin receptor substrate 2b.
    
 0.978
LOC107089487
Insulin-like growth factor 2b.
    
 0.977
LOC107091852
Uncharacterized protein.
    
 0.970
LOC107094114
Growth factor receptor-bound protein 10b.
    
 0.970
Your Current Organism:
Cyprinodon variegatus
NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow
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