Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC107089511Potassium channel tetramerization domain containing 2. (267 aa)    
Predicted Functional Partners:
LOC107099750
CULLIN_2 domain-containing protein; Belongs to the cullin family.
    
 0.931
CUL3
Cullin 3; Belongs to the cullin family.
    
 0.931
ranbp2
RAN binding protein 2.
   
 0.929
sae1
SUMO1 activating enzyme subunit 1.
  
 0.918
kctd9
Potassium channel tetramerization domain containing 9a.
    
 
 0.918
sumo1
Small ubiquitin-related modifier.
   
 0.908
uba2
SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family.
   
 0.906
nsmce2
NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase.
   
 0.904
pcna
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 0.900
rad52
RAD52 homolog, DNA repair protein.
    
 0.868
Your Current Organism:
Cyprinodon variegatus
NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow
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