Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
appl2Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2. (609 aa)    
Predicted Functional Partners:
APPL1
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1.
    
 
 0.963
akt1
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
 
 0.890
LOC107099926
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
 
 0.890
LOC107083482
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
 
 0.890
ENSCVAP00000029198
V-akt murine thymoma viral oncogene homolog 3b.
    
 
 0.890
neo1
Neogenin 1b.
    
 0.834
Igdcc4
Uncharacterized protein.
    
 0.831
igdcc3
Immunoglobulin superfamily, DCC subclass, member 3.
    
 0.831
LOC107087973
Uncharacterized protein.
    
 0.831
ENSCVAP00000028331
Uncharacterized protein.
    
 0.831
Your Current Organism:
Cyprinodon variegatus
NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow
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