node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
cdc45 | cdc6 | ENSCVAP00000015110 | ENSCVAP00000027611 | CDC45 cell division cycle 45 homolog (S. cerevisiae). | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | 0.958 |
cdc45 | cdt1 | ENSCVAP00000015110 | ENSCVAP00000022727 | CDC45 cell division cycle 45 homolog (S. cerevisiae). | Chromatin licensing and DNA replication factor 1. | 0.952 |
cdc45 | mcm10 | ENSCVAP00000015110 | ENSCVAP00000001606 | CDC45 cell division cycle 45 homolog (S. cerevisiae). | Minichromosome maintenance 10 replication initiation factor. | 0.996 |
cdc45 | mcm2 | ENSCVAP00000015110 | ENSCVAP00000030737 | CDC45 cell division cycle 45 homolog (S. cerevisiae). | DNA helicase; Belongs to the MCM family. | 0.999 |
cdc45 | mcm3 | ENSCVAP00000015110 | ENSCVAP00000002787 | CDC45 cell division cycle 45 homolog (S. cerevisiae). | DNA helicase; Belongs to the MCM family. | 0.999 |
cdc45 | mcm4 | ENSCVAP00000015110 | ENSCVAP00000028976 | CDC45 cell division cycle 45 homolog (S. cerevisiae). | DNA helicase; Belongs to the MCM family. | 0.999 |
cdc45 | mcm5 | ENSCVAP00000015110 | ENSCVAP00000001188 | CDC45 cell division cycle 45 homolog (S. cerevisiae). | DNA helicase; Belongs to the MCM family. | 0.999 |
cdc45 | mcm6 | ENSCVAP00000015110 | ENSCVAP00000031037 | CDC45 cell division cycle 45 homolog (S. cerevisiae). | DNA helicase; Belongs to the MCM family. | 0.999 |
cdc45 | mcm7 | ENSCVAP00000015110 | ENSCVAP00000000768 | CDC45 cell division cycle 45 homolog (S. cerevisiae). | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | 0.999 |
cdc45 | orc2 | ENSCVAP00000015110 | ENSCVAP00000013167 | CDC45 cell division cycle 45 homolog (S. cerevisiae). | Origin recognition complex, subunit 2. | 0.966 |
cdc6 | cdc45 | ENSCVAP00000027611 | ENSCVAP00000015110 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | CDC45 cell division cycle 45 homolog (S. cerevisiae). | 0.958 |
cdc6 | cdt1 | ENSCVAP00000027611 | ENSCVAP00000022727 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | Chromatin licensing and DNA replication factor 1. | 0.999 |
cdc6 | mcm10 | ENSCVAP00000027611 | ENSCVAP00000001606 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | Minichromosome maintenance 10 replication initiation factor. | 0.992 |
cdc6 | mcm2 | ENSCVAP00000027611 | ENSCVAP00000030737 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | DNA helicase; Belongs to the MCM family. | 0.999 |
cdc6 | mcm3 | ENSCVAP00000027611 | ENSCVAP00000002787 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | DNA helicase; Belongs to the MCM family. | 0.999 |
cdc6 | mcm4 | ENSCVAP00000027611 | ENSCVAP00000028976 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | DNA helicase; Belongs to the MCM family. | 0.999 |
cdc6 | mcm5 | ENSCVAP00000027611 | ENSCVAP00000001188 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | DNA helicase; Belongs to the MCM family. | 0.999 |
cdc6 | mcm6 | ENSCVAP00000027611 | ENSCVAP00000031037 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | DNA helicase; Belongs to the MCM family. | 0.999 |
cdc6 | mcm7 | ENSCVAP00000027611 | ENSCVAP00000000768 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | 0.999 |
cdc6 | orc2 | ENSCVAP00000027611 | ENSCVAP00000013167 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | Origin recognition complex, subunit 2. | 0.999 |