STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nuak1NUAK family, SNF1-like kinase, 1b. (642 aa)    
Predicted Functional Partners:
stk11
Serine/threonine kinase 11; Belongs to the protein kinase superfamily.
  
 
0.698
nt5dc3
5'-nucleotidase domain containing 3.
      
 0.499
LOC107092181
Bac_surface_Ag domain-containing protein.
      
 0.499
pik3c2a
Phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha; Belongs to the PI3/PI4-kinase family.
      
 0.499
api5
Apoptosis inhibitor 5.
      
 0.491
ccbe1
Collagen and calcium binding EGF domains 1.
      
 0.485
tp53
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
    
 0.404
Your Current Organism:
Cyprinodon variegatus
NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow
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