Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
LOC107097278Paxillin; Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Belongs to the paxillin family. (542 aa)    
Predicted Functional Partners:
LOC107084591
Vinculin a.
   
 0.864
ENSCVAP00000021860
Uncharacterized protein.
   
 0.864
vcl
Vinculin b.
   
 0.864
LOC107101152
Parvin, alpha a.
   
 0.858
parvb
Parvin, beta.
   
 0.847
LOC107096201
Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family.
    
 0.788
LOC107088538
Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.
    
 0.788
crk
CRK proto-oncogene, adaptor protein.
    
 0.759
LOC107081852
Uncharacterized protein.
    
 0.759
crkl
V-crk avian sarcoma virus CT10 oncogene homolog-like.
    
 0.759
Your Current Organism:
Cyprinodon variegatus
NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow
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