Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
twf1Twinfilin actin-binding protein 1a. (350 aa)    
Predicted Functional Partners:
capzb
F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
   
 0.901
LOC107090391
Glia maturation factor; Belongs to the actin-binding proteins ADF family. GMF subfamily.
   
 
 0.724
cap1
Adenylyl cyclase-associated protein; Belongs to the CAP family.
   
 
 0.723
cap2
Adenylyl cyclase-associated protein; Belongs to the CAP family.
   
 
 0.723
wdr82
WD repeat domain 82.
 
      0.703
mtpn
ANK_REP_REGION domain-containing protein.
    
 0.648
GRXCR2
Glutaredoxin and cysteine rich domain containing 2.
     
 0.629
tmod3
Tropomodulin 2.
   
 0.624
bcl7a
BAF chromatin remodeling complex subunit BCL7A.
    
   0.612
CAPZA2
F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
   
 0.601
Your Current Organism:
Cyprinodon variegatus
NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow
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