Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
LOC107098490G_PROTEIN_RECEP_F1_2 domain-containing protein. (685 aa)    
Predicted Functional Partners:
TSHB
Thyroid stimulating hormone subunit beta.
    
 0.968
LOC107101308
Thyroid stimulating hormone subunit beta a.
    
 0.968
gpha2
Glycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family.
    
 0.962
gphb5
Glycoprotein hormone subunit beta 5.
     
 0.961
LOC107084142
Si:dkey-23i12.9.
     
 0.960
cga
Glycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family.
   
 
 0.906
tshr
Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.
  
  
 
0.904
Fshb
Cys_knot domain-containing protein.
   
 0.852
GNAS
GNAS complex locus.
    
 0.766
LOC107103230
GNAS complex locus.
    
 0.766
Your Current Organism:
Cyprinodon variegatus
NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow
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