Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PDZRN4PDZ domain containing ring finger 4. (616 aa)    
Predicted Functional Partners:
mib2
Mindbomb E3 ubiquitin protein ligase 2.
    
 0.755
LOC107091989
Receptor-interacting serine-threonine kinase 3.
   
 0.685
ripk4
Receptor-interacting serine-threonine kinase 4.
   
 0.685
birc6
Baculoviral IAP repeat containing 6.
   
 0.667
Birc6
UBIQUITIN_CONJUGAT_2 domain-containing protein.
   
 0.667
LOC107090723
Ubiquitin-conjugating enzyme E2 variant 1.
   
 0.615
LOC107102357
ECSIT signalling integrator.
    
 0.590
ankrd22
Ankyrin repeat domain 22.
    
 0.581
rps27a
Ribosomal protein S27a.
    
 0.564
tradd
Tnfrsf1a-associated via death domain.
    
 0.563
Your Current Organism:
Cyprinodon variegatus
NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow
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