STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPRED2Sprouty related EVH1 domain containing 2. (465 aa)    
Predicted Functional Partners:
nf1
Neurofibromin 1b.
    
 0.899
CACNA1D
Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.
      
 0.662
nek2
NIMA-related kinase 2.
    
 0.651
CSDE1
Cold shock domain containing E1, RNA-binding.
   
 0.576
LOC107095138
Zgc:55558.
   
 0.576
KRAS
V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog.
   
 0.576
hras
HRas proto-oncogene, GTPase a.
   
 0.576
LOC107096025
Uncharacterized protein.
   
 0.560
LOC107095444
V-ral simian leukemia viral oncogene homolog Ba (ras related).
   
 0.560
LOC107099411
V-ral simian leukemia viral oncogene homolog Aa (ras related).
   
 0.560
Your Current Organism:
Cyprinodon variegatus
NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.