eif2ak3 protein (Cyprinodon variegatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

eif2ak3

Eukaryotic translation initiation factor 2-alpha kinase 3. (1100 aa)

Predicted Functional Partners:

eif2s1

0.994

LOC107090074

0.961

EIF2AK4

0.952

atf4

0.952

hspa5

0.952

eif2ak1

0.938

LOC107082057

0.928

nfe2

0.918

eif2s2

0.728

eif2s3

0.727

Your Current Organism:

Cyprinodon variegatus

NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EIF2AK4	LOC107082057	ENSCVAP00000016023	ENSCVAP00000001804	Eukaryotic translation initiation factor 2 alpha kinase 4.	Nuclear factor, erythroid 2-like 2a.	0.907
EIF2AK4	LOC107090074	ENSCVAP00000016023	ENSCVAP00000004441	Eukaryotic translation initiation factor 2 alpha kinase 4.	Activating transcription factor 4a.	0.555
EIF2AK4	atf4	ENSCVAP00000016023	ENSCVAP00000021357	Eukaryotic translation initiation factor 2 alpha kinase 4.	Activating transcription factor 4b.	0.551
EIF2AK4	eif2ak1	ENSCVAP00000016023	ENSCVAP00000030328	Eukaryotic translation initiation factor 2 alpha kinase 4.	Eukaryotic translation initiation factor 2-alpha kinase 1.	0.926
EIF2AK4	eif2ak3	ENSCVAP00000016023	ENSCVAP00000001887	Eukaryotic translation initiation factor 2 alpha kinase 4.	Eukaryotic translation initiation factor 2-alpha kinase 3.	0.952
EIF2AK4	eif2s1	ENSCVAP00000016023	ENSCVAP00000021409	Eukaryotic translation initiation factor 2 alpha kinase 4.	Eukaryotic translation initiation factor 2, subunit 1 alpha b.	0.994
EIF2AK4	eif2s2	ENSCVAP00000016023	ENSCVAP00000000921	Eukaryotic translation initiation factor 2 alpha kinase 4.	Eukaryotic translation initiation factor 2, subunit 2 beta.	0.833
EIF2AK4	eif2s3	ENSCVAP00000016023	ENSCVAP00000013490	Eukaryotic translation initiation factor 2 alpha kinase 4.	Eukaryotic translation initiation factor 2, subunit 3 gamma.	0.872
EIF2AK4	hspa5	ENSCVAP00000016023	ENSCVAP00000029709	Eukaryotic translation initiation factor 2 alpha kinase 4.	Heat shock protein 5; Belongs to the heat shock protein 70 family.	0.440
EIF2AK4	nfe2	ENSCVAP00000016023	ENSCVAP00000026806	Eukaryotic translation initiation factor 2 alpha kinase 4.	Nuclear factor, erythroid 2.	0.904
LOC107082057	EIF2AK4	ENSCVAP00000001804	ENSCVAP00000016023	Nuclear factor, erythroid 2-like 2a.	Eukaryotic translation initiation factor 2 alpha kinase 4.	0.907
LOC107082057	LOC107090074	ENSCVAP00000001804	ENSCVAP00000004441	Nuclear factor, erythroid 2-like 2a.	Activating transcription factor 4a.	0.514
LOC107082057	eif2ak1	ENSCVAP00000001804	ENSCVAP00000030328	Nuclear factor, erythroid 2-like 2a.	Eukaryotic translation initiation factor 2-alpha kinase 1.	0.901
LOC107082057	eif2ak3	ENSCVAP00000001804	ENSCVAP00000001887	Nuclear factor, erythroid 2-like 2a.	Eukaryotic translation initiation factor 2-alpha kinase 3.	0.928
LOC107082057	nfe2	ENSCVAP00000001804	ENSCVAP00000026806	Nuclear factor, erythroid 2-like 2a.	Nuclear factor, erythroid 2.	0.929
LOC107090074	EIF2AK4	ENSCVAP00000004441	ENSCVAP00000016023	Activating transcription factor 4a.	Eukaryotic translation initiation factor 2 alpha kinase 4.	0.555
LOC107090074	LOC107082057	ENSCVAP00000004441	ENSCVAP00000001804	Activating transcription factor 4a.	Nuclear factor, erythroid 2-like 2a.	0.514
LOC107090074	atf4	ENSCVAP00000004441	ENSCVAP00000021357	Activating transcription factor 4a.	Activating transcription factor 4b.	0.908
LOC107090074	eif2ak3	ENSCVAP00000004441	ENSCVAP00000001887	Activating transcription factor 4a.	Eukaryotic translation initiation factor 2-alpha kinase 3.	0.961
LOC107090074	eif2s1	ENSCVAP00000004441	ENSCVAP00000021409	Activating transcription factor 4a.	Eukaryotic translation initiation factor 2, subunit 1 alpha b.	0.961