STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
rngttPolynucleotide 5'-triphosphatase; Bifunctional mRNA-capping enzyme exhibiting RNA 5'- triphosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the gmp moiety of GTP to the 5'-diphosphate terminus. (601 aa)    
Predicted Functional Partners:
rnmt
mRNA cap guanine-N7 methyltransferase.
   
 0.995
supt5h
Transcription elongation factor SPT5.
    
 0.990
polr2a
DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 0.941
polr2g
Polymerase (RNA) II (DNA directed) polypeptide G-like.
    
  0.940
polr2d
Polymerase (RNA) II (DNA directed) polypeptide D.
    
 0.937
ENSCVAP00000006489
Uncharacterized protein.
    
 0.929
nup50
Nucleoporin 50.
    
   0.929
LOC107099697
RPOLD domain-containing protein.
   
 0.906
POLR2C
Polymerase (RNA) II (DNA directed) polypeptide C.
   
 0.906
polr2j
Polymerase (RNA) II (DNA directed) polypeptide J.
    
  0.902
Your Current Organism:
Cyprinodon variegatus
NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow
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