Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC107093166Tribbles pseudokinase 3. (350 aa)    
Predicted Functional Partners:
LOC107090074
Activating transcription factor 4a.
   
 0.979
cop1
COP1 E3 ubiquitin ligase.
    
 
 0.965
stk40
Serine/threonine kinase 40.
    
 
 0.963
sqstm1
Sequestosome 1.
    
 
 0.902
LOC107083482
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
 0.886
LOC107097093
Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.
   
 
 0.880
chac1
Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.
   
 
 0.880
akt1
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
 0.855
LOC107099926
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
 0.855
ENSCVAP00000029198
V-akt murine thymoma viral oncogene homolog 3b.
    
 0.855
Your Current Organism:
Cyprinodon variegatus
NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow
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