STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tyrp1Tyrosinase related protein 1. (525 aa)    
Predicted Functional Partners:
Mc1r
Melanocyte-stimulating hormone receptor.
    
 0.945
slc24a5
Solute carrier family 24 member 5; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
      
 0.915
dct
Dopachrome tautomerase.
  
  
 
0.902
oca2
Oculocutaneous albinism II.
      
 0.894
LOC107082335
Melanocyte inducing transcription factor a.
    
 0.880
txnl4b
Thioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family.
      
 0.853
LOC107096661
SRY-box transcription factor 10.
    
 
 0.821
pmel
Premelanosome protein a.
   
 
 0.748
slc45a2
Solute carrier family 45 member 2.
      
 0.697
pax3
Paired box 3b.
    
 
 0.685
Your Current Organism:
Cyprinodon variegatus
NCBI taxonomy Id: 28743
Other names: C. variegatus, sheepshead minnow
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.